Decreased mRNA Expression of Cystathionine Gamma lyase and H2S Concentration in Gastric Mucosal Tissue in Diabetic Rats

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Duodenal acidification stimulates gastric H2S release through upregulating mRNA expression of cystathionine gamma lyase

Introduction: It has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of H2S, but till now the effect of duodenal acidification on gastric H2S release has not been investigated. Therefore, the present study designed to evaluate the effects of duodenal acidification on gastric H2S release and level of mRNA expression of cys...

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duodenal acidification stimulates gastric h2s release through upregulating mrna expression of cystathionine gamma lyase

introduction: it has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of h2s, but till now the effect of duodenal acidification on gastric h2s release has not been investigated. therefore, the present study designed to evaluate the effects of duodenal acidification on gastric h2s release and level of mrna expression of cystath...

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Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

Objective(s): This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase (CBS), and mucosal release of H2S in gastric mucosa in rats. Materials and Methods:Thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, HCl (10 mM) treated g...

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Effect of Thyrotoxicosis on Gene Expression of Hydrogen Sulfide-producing Enzymes in Epididymal Adipose Tissue of Male Rats

Introduction: Thyroid hormones are involved in the regulation of hydrogen sulfide (H2S) biosynthesis. The aim of this study is to determine effects of thyrotoxicosis on H2S levels and mRNA expression of cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST) in the adipose tissue of rat. Materials and Methods: Male rats were divided into the ...

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mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

objective(s): this study was performed to investigate the effects of mucosal acidification on mrna expression and protein synthesis of cystathionine gamma lyase (cse), cystathionine beta synthase (cbs), and mucosal release of h2s in gastric mucosa in rats. materials and methods:thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, hcl (10 mm) treated gr...

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ژورنال

عنوان ژورنال: Brazilian Archives of Biology and Technology

سال: 2018

ISSN: 1678-4324,1516-8913

DOI: 10.1590/1678-4324-2018160308